iBox® SCIENTIA SMALL ANIMAL IMAGING SYSTEM
iBox® Scientia Small Animal
Imaging System is designed to automate your in vivo small animal imaging
research with one-touch, pre-set or user-defined PC controls for accurate,
repeatable imaging. Capture superior small animal images with the high
resolution, high sensitivity cooled CCD camera and optics.
UVP is partnering with Anticancer, Inc. for fluorescent protein
in vivo small animal imaging technology! UVP's innovative world
class iBox Scientia system provides researchers with access to
extensive techniques and applications technology from
Anticancer, Inc., equipping labs with comprehensive tools for
small animal in vivo fluorescent imaging.
APPLICATIONS
Small animal in vivo imaging of:
Tumor
studies 
Cancer research
Heart disease
Gene therapy
Optional mouse anesthesia
units available with
single station or five-port manifold. See Options for
details.
SPECIFICATIONS
Darkroom:
Light tight
Wide access door with UV safety shutoff
Gel viewing window
Sliding tray for optional Transilluminator
Epi white and UV illumination (365nn and 480nm)
Emission Filters - five positions:
SYBR Green 515-570nm
SYBR Gold 485-655nm
EtBr Red 570-640nm
Clear
Open
BioLite MultiSpectral Source
Power source housing external to darkroom
150 watt light source
Fiber optic bundles connect to either epi or transillumination light sources
Eight excitation filter positions
Manual or software controlled
Software:
Interface for automated controls
VisionWorksLS Acquisition and Analysis Software (system may be configured with software or optional, check with your UVP representative)
Windows 2000 SP4, Windows XP Pro SP2
OPTIONS
Anesthesia Units:
Optional anesthesia equipment
provides easy-connect, dedicated ports for inlet and
outlet isoflurane gas lines. The heat controlled
warmer plate maintains a constant temperature for
prevention of mouse hypothermia. Multiple-port
manifold allows up to three at one time. A pull-out
tray in the darkroom enables hassle-free placement
of mice in the darkroom chamber. The anesthesia
system features patented rebreathing technology.
Custom and standard excitation and emission filter sets
Thermal Printer: For archive quality prints in seconds
LED White Light Tray
Warming Tray
Bench top and FirstLight UV transilluminator's
Computer and monitor
| SYSTEM NAMES | CAMERA | PRICE |
| iBox Scientia 500 Imaging System | Bio-Chemi HR 500 | $ |
| iBox SCIENTIA 600 Imaging System | OptiChemi 600 | $ |
The
Advantages of Fluorescent Proteins Over Luciferase for
In Vivo Imaging
Salmonella
Typhimurium Treatment of RFP Tagged U87 Tumors in Nude
Mice (AntiCancer, Inc.)
Fast Imaging System with Maximized Flexibility for Fluorescent Protein Imaging In Vivo
USP 6,232,523 , Metastasis models using green florescent protein (GFP) as a marker
USP 6,649,159, Whole-body optical imaging of gene expression and uses thereof
USP 6,235,968, Metastasis models using green fluorescent protein (GFP) as a marker
USP 6,251,384, Metastasis models using green fluorescent protein (GFP) as a marker
USP 6,759,038, Metastasis models using green fluorescent protein (GFP) as a marker
USP 6,905,831, Real time measurement of cellular responses
Australia 749,338, Metastasis models using green fluorescent protein (GFP) as a marker
Australia 2001249297, Whole-body optical imaging of gene expression and uses thereof
Japan 3,709,343, Metastasis model using green fluorescent protein (GFP) as a marker
Japan 4,021,197, Whole-body optical imaging of gene expression and uses thereof
Imaging
cancer dynamics in vivo at the tumor and cellular
level with fluorescent proteins, Robert M. Hoffman,
Clin Exp Metastasis (2009) 26:345–355
The Cyan Fluorescent Protein (CFP) Transgenic Mouse
as a Model for Imaging Pancreatic Exocrine Cells
Journal: JOP. J Pancreas (Online) 2009;
10(2):152-156. JOP.J Pancreas (Online) 2009.
The multiple uses of fluorescent proteins to
visualize cancer in vivo. Nature Reviews Cancer,
2005. Hoffman, R.M. Res. 5, 796-806.
Whole-body imaging of bacterial infection and
antibiotic response. Nature Protocols 1(6),
2988-2994, 2007.
Chemotherapy targets the hair-follicle vascular
network but not the stem cells. J. Invest. Dermatol.
127, 11-15, 2007
Photodynamic therapy of
rhabdomyosarcoma. Int. J. Oncol. 30, 615-620, 2007
Whole-body sub cellular
multicolor imaging. Proc. of SPIE 6449,
64490V1-64490V9, 2007
Preclinical fluorescent mouse models of pancreatic
cancer. Proc. of SPIE 6449, 64490X1-64490X11, 2007
GFP-expressing vascularization of Gel foam as a
rapid in vivo assay of angiogenesis stimulators and
inhibitors. BioTechniques 42, 294-298, 2007.
Noninvasive imaging for evaluation of the systemic
delivery of capsid-modified adenovirus in an
orthotopic model of advanced lung cancer. Cancer
109, 1213-1214, 2007.
The camptothecin derivative CPT-11 inhibits
angiogenesis in a dual-color image able orthotopic
metastatic nude mouse model of human colon cancer.
Anticancer Res. 27, 713-718, 2007.
Whole-body sub cellular multicolor imaging of
tumor-host interaction and drug response in real
time. Cancer Res. 67, 5195-5200, 2007.
Dual-color imaging of angiogenesis and its
inhibition in bone and soft tissue sarcoma. J. Surg.
Res. 140, 165-170, 2007.
Monotherapy with a tumor-targeting mutant of
Salmonella typhimurium cures orthotopic metastatic
mouse models of human prostate cancer. Proc. Natl.
Acad. Sci. USA 104, 10170-10174, 2007.
Mutant PIK3CA-bearing colon cancer cells display
increased metastasis in an orthotopic model. Cancer
Res. 67, 5851-5858, 2007.
An image able metastatic treatment model of
nasopharyngeal carcinoma. Clin. Cancer Res. 13,
3960-3967, 2007.
A novel alkylating agent, glufosfamide, enhances the
activity of gemcitabine in vitro and in vivo.
Neoplasia 9, 625-633, 2007.
Real-time imaging of tumor-cell shedding and
trafficking in lymphatic channels. Cancer Res. 67,
8223-8228, 2007.
Sub cellular imaging of cancer calls in live mice.
In: Reporter Genes: A Practical Guide, Voll. 411,
pp. 121-130, Methods in Molecular Biology series,
Anson, D.S., editor. Humana Press, 2007.
A better fluorescent protein for whole-body imaging.
Trends in Biotechnology 26, 1-3, 2008.
Induction of cancer metastasis by cyclophosphamide
pretreatment of host mice: an opposite effect of
chemotherapy. Cancer Res. 68, 516-520, 2008.
Imaging in mice with fluorescent proteins: from
macro to sub cellular. Sensors 8, 1157-1173, 2008.
Imaging of cell trafficking and metastasis of
pediatric rhabdomyosarcoma. Cell Proliferation 41,
365-374, 2008.
Characterization of HCT116 human colon cancer cells
in an orthotopic model. J. Surg. Res. 147, 276-281,
2008.
Biomimetic amplification of nanoparticle homing to
tumors. Proc. Natl. Acad. Sci. USA 104, 932-936,
2007.
Since 1988 Nation Enterprises,
and since 1993 Lapidary Rock Shop has been providing the highest quality
products and services to the lapidary market.
1-800-820-3612
E-MAIL: russ@rnbrockshop.com
Copyright© 1998/2010 ®NATION ENTERPRISES
Owned and operated by Russ & Betty Nation
NEW: 08-24-1998
Completely Revised: 11-12-2000
COMPLETE REVISION 05/2007
REV: 10/06/2010